Journal title
عنوان نشریه
Journal of Dentomaxillofacial
Literature & Humanities
http://3dj.gums.ac.ir
1
admin
doi
en
jalali
1401
4
1
gregorian
2022
7
1
11
3
online
1
fulltext
en
Research Paper: Xerostomia in Schizophrenia and Bipolar Patients: Is There Any Relation?
عمومى
General
پژوهشي
Original article
Abstract<br>
Introduction: Psychiatric disorders such as bipolar disorder and schizophrenia cause vascular, neurological, and neurobiological changes. On other hand, salivary glands are influenced by changes in the autonomic nervous system. Therefore, this <br>
hypothesis was formed that psychiatric disorders can affect salivary glands through neurological pathways. This study aimed to evaluate if schizophrenia and bipolar disorder can cause xerostomia and lip dryness in patients who are not using psychiatric drugs.<br>
Materials and Methods: This study included 54 bipolar and 50 schizophrenia whose disorder was confirmed, and the control group included 60 healthy individuals whose mental health was evaluated through GHQ21 questionnaire and a psychiatrist. The FOX questionnaire was also completed to diagnose Xerostomia and lip dryness. Data were analyzed by SPSS version 22 using Chi-square, t-independent, logistic <br>
regression, ANOVA, Tukey test, Kruskal–Wallis, Mann–Whitney and Spearman <br>
correlation.<br>
Results: In this study, xerostomia was found in the bipolar group (57/40%), <br>
schizophrenia group (66%) and control group (18/33%). Xerostomia and dry lips were significantly higher in psychiatric patients than in the control group, but there was no significant difference between bipolar patients and schizophrenia patients. In this study, there was no significant relationship between Xerostomia and age and gender.<br>
Conclusion: Neurological changes are factors that affect salivary secretions causing Xerostomia. Dentists must always consider psychological factors as a causative agent of Xerostomia.<br>
Oral Manifestation,
Lip dryness, Xerostomia
26
33
http://3dj.gums.ac.ir/browse.php?a_code=A-10-382-54&slc_lang=en&sid=1
Maryam
Basirat
https://orcid.org/0000-0003-1671-7279
No
Dental Sciences Research Center, Department of Oral and Maxillofacial Medicine, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran.
Robabe
Soleimani
0000-0003-0936-5981
No
Kavosh Behavioral, Cognitive and Addiction Research Center, the Department of Psychiatry, Shafa Hospital, Guilan University of Medical Sciences, Rasht, Iran.
Dina
Maleki
Dinamaleki74@gmail.com
https://orcid.org/0000-0002-8492-618X
Yes
Student Research Committee, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran.
Elahe
Alipour
https://orcid.org/0000-0001-7281-0481
No
DDS.
Sattar
Akbari
0000-0003-2621-1896
No
Orthodontics department, School of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.