Journal title
عنوان نشریه
Journal of Dentomaxillofacial
Literature & Humanities
http://3dj.gums.ac.ir
1
admin
doi
en
jalali
1397
12
1
gregorian
2019
3
1
8
1
online
1
fulltext
en
Candida Albicans detection in pre-malignant and malignant lesions of the oral cavity
عمومى
General
پژوهشي
Original article
Abstract<br>
<br>
Introduction: Nowadays, there is a remarkably increase of the interest of Candida Albicans studies mainly because of its relation with potentially malignant and malignant lesions of the oral cavity. In the present study we aim to reveal if there are any differences between these lesions or not.<br>
Materials and Methods:Totally 72 patient consist of 23 leukoplakia, 18 oral lichen planus, 13 well differentiated squamous cell carcinoma (WSCC), 13 moderate squamous cell carcinoma (MSCC) and 5 undifferentiated squamous cell carcinoma were included in this cross-sectional analytical study. These samples were then gone under PAS staining and statistically analyze with Mann Whitney, Chi-square (p˂0.05).<br>
Results:The results showed significantly differences between dysplastic and non-dysplastic epithelium (P=0.008), but there are no statistically significant differences between various degrees of oral squamous cell carcinoma (OSCC) (P=0.26), even though there were differences.<br>
Conclusion: The present results confirms the previous studies on the correlation between malignant lesions and the presence of fungi hyphae, but further studies are needed.<br>
Candida albicans
Periodic Acid-Schiff Reaction
Carcinoma, Squamous Cell
26
30
http://3dj.gums.ac.ir/browse.php?a_code=A-10-382-5&slc_lang=en&sid=1
Nazanin
Bashardoust
https://orcid.org/ 0000-0002-9969-8087
No
Assistant professor, department of oral and maxillofacial pathology, school of dentistry, Guilan University of Medical Sciences, Rasht, Iran
Mohadese
Asli
https://orcid.org/ 0000-0001-7859-0838
No
Dentistry student, Guilan University of Medical Sciences, Rasht, Iran
Atesa
Faeghi Raad
No
Dentist
Masoumeh
Soudeh Sarabi
No
Dentist
Shirin
Modabbernia
https://orcid.org/ 0000-0001-7984-0878
Yes
Assistant professor, department of oral and maxillofacial pathology, school of dentistry, Guilan University of Medical Sciences, Rasht, Iran