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Volume 14, Issue 3 (9-2025)
2025, 14(3): 8-14 |
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Asadi Aria A, Simdar N, Hajibagheri P. Low-level Laser Therapy in Direct Pulp Capping: A Narrative Review of Randomized Controlled Trials. Journal title 2025; 14 (3) :8-14
URL: http://3dj.gums.ac.ir/article-1-665-en.html
URL: http://3dj.gums.ac.ir/article-1-665-en.html
1- Student Research Committee, School of Anzali International Campus, Guilan University of Medical Sciences, Rasht, Iran.
2- Department of Endodontics, Dental Sciences Research Center, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran.
3- Department of Oral and Maxillofacial Medicine, Dental Sciences Research Center, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran. ,hajibagheripedram@gmail.com
2- Department of Endodontics, Dental Sciences Research Center, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran.
3- Department of Oral and Maxillofacial Medicine, Dental Sciences Research Center, School of Dentistry, Guilan University of Medical Sciences, Rasht, Iran. ,
Abstract: (217 Views)
Direct pulp capping (DPC) preserves pulp vitality after caries exposure by applying biocompatible materials, such as mineral trioxide aggregate (MTA), biodentine, or calcium hydroxide to stimulate reparative dentin formation. Low-level laser therapy (LLLT) has emerged as a promising adjunct that reduces inflammation and accelerates dentinogenesis. Laser technology continues to evolve, with newer devices offering improved energy delivery and enhanced biological responses. Recognizing these advancements, our narrative review of randomized controlled trials aimed to integrate the most recent evidence to provide an updated understanding of LLLT’s efficiency in DPC by synthesizing available clinical data, clarifying key influencing factors, and identifying priorities for future research. Six randomized controlled trials comprising 268 permanent teeth were included based on comprehensive database searches up to November 2025. These studies compared LLLT-assisted DPC against standard methods in caries-exposed teeth, emphasizing clinical, radiographic, and histological outcomes and excluding non-RCTs or animal studies. LLLT demonstrated high clinical success in most studies and was associated with thicker, more complete dentin bridges, reduced inflammation, enhanced apical maturation in immature teeth, and better pain relief—especially when combined with MTA, Biodentine, or MTA+ platelet-rich fibrin (PRF). Although the benefits are clear, variability in laser parameters, small sample sizes, and short follow-up periods limit broader conclusions. Standardized, large-scale, long-term RCTs are essential to refine protocols and enable LLLT’s routine use in vital pulp therapy.
Type of Study: Review article |
Subject:
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Received: 2025/11/20 | Accepted: 2025/12/16 | Published: 2025/09/15
Received: 2025/11/20 | Accepted: 2025/12/16 | Published: 2025/09/15
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