Volume 8, Issue 1 (3-2019)                   3dj 2019, 8(1): 26-30 | Back to browse issues page

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Bashardoust N, Asli M, Faeghi Raad A, Soudeh Sarabi M, Modabbernia S. Candida Albicans detection in pre-malignant and malignant lesions of the oral cavity. 3dj 2019; 8 (1) :26-30
URL: http://3dj.gums.ac.ir/article-1-461-en.html
1- Assistant professor, department of oral and maxillofacial pathology, school of dentistry, Guilan University of Medical Sciences, Rasht, Iran
2- Dentistry student, Guilan University of Medical Sciences, Rasht, Iran
3- Dentist
Abstract:   (334 Views)

Introduction: Nowadays, there is a remarkably increase of the interest of Candida Albicans studies mainly because of its relation with potentially malignant and malignant lesions of the oral cavity. In the present study we aim to reveal if there are any differences between these lesions or not.
Materials and Methods:Totally 72 patient consist of 23 leukoplakia, 18 oral lichen planus, 13 well differentiated squamous cell carcinoma (WSCC), 13 moderate squamous cell carcinoma (MSCC) and 5 undifferentiated squamous cell carcinoma were included in this cross-sectional analytical study. These samples were then gone under PAS staining and statistically analyze with Mann Whitney, Chi-square (p˂0.05).
Results:The results showed significantly differences between dysplastic and non-dysplastic epithelium (P=0.008), but there are no statistically significant differences between various degrees of oral squamous cell carcinoma (OSCC) (P=0.26), even though there were differences.
Conclusion: The present results confirms the previous studies on the correlation between malignant lesions and the presence of fungi hyphae, but further studies are needed.
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Type of Study: Original article | Subject: General
Received: 2021/12/4 | Accepted: 2019/03/2 | Published: 2019/03/2

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